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                     July 15, 2022

       Keith D. Taylor
       Chief Financial Officer
       Equinix Inc.
       One Lagoon Drive
       Redwood City, CA 94065

                                                        Re: Equinix Inc.
                                                            Form 10-K for the
year ended December 31, 2021
                                                            Filed February 18,
2022
                                                            File No. 001-40205

       Dear Mr. Taylor:

              We have completed our review of your filing. We remind you that
the company and its
       management are responsible for the accuracy and adequacy of their
disclosures, notwithstanding
       any review, comments, action or absence of action by the staff.




                     Sincerely,


                     Division of Corporation Finance

                     Office of Real Estate & Construction