Exhibit 5.2

Davis Polk & Wardwell llp 1600 El Camino Real Menlo Park, CA 94025 davispolk.com

March 18, 2024

Equinix, Inc.

One Lagoon Drive

Redwood City, California 94065

Equinix Europe 2 Financing Corporation LLC

One Lagoon Drive

Redwood City, California 94065

Ladies and Gentlemen:

Equinix, Inc., a Delaware corporation (“Equinix”), and Equinix Europe 2 Financing Corporation LLC, a Delaware limited liability company (“Equinix Europe 2 Finco”), are filing with the Securities and Exchange Commission a Post-Effective Amendment No. 1 (the “Post-Effective Amendment”) to the Registration Statement on Form S-3 (File No. 333-275203) filed with the Securities and Exchange Commission on October 27, 2023 (the “Initial Registration Statement”) for the purpose of (a) adding Equinix Europe 2 Finco, a wholly-owned subsidiary of Equinix, as a co-registrant; (b) registering under the Securities Act of 1933, as amended (the “Securities Act”) (i) debt securities of Equinix Europe 2 Finco (the “Debt Securities”) and (ii) full and unconditional guarantees by Equinix of the Debt Securities (the “Guarantees”), in each case to be issued pursuant to the indenture, dated as of March 18, 2024 (the “Base Indenture”), between Equinix Europe 2 Finco, Equinix, and U.S. Bank Trust Company, National Association, as trustee (the “Trustee”); and (c) including an at-the-market offering prospectus supplement (the “ATM Prospectus Supplement”) relating to the shares of Equinix common stock, par value $0.001 per share (“Common Stock”) having an aggregate offering price of up to $469,667,030 that remain available to be sold as of the filing date of the Post-Effective Amendment pursuant to that certain equity distribution agreement by and among Equinix, the Managers, the Forward Purchasers, and the Forward Sellers named therein, dated November 4, 2022, as amended on October 27, 2023 (as amended, the “Equity Distribution Agreement”).

We, as your counsel, have examined originals or copies of such documents, corporate records, certificates of public officials and other instruments as we have deemed necessary or advisable for the purpose of rendering this opinion.

In rendering the opinions expressed herein, we have, without independent inquiry or investigation, assumed that (i) all documents submitted to us as originals are authentic and complete, (ii) all documents submitted to us as copies conform to authentic, complete originals, (iii) all documents filed as exhibits to the Post-Effective Amendment that have not been executed will conform to the forms thereof, (iv) all signatures on all documents that we reviewed are genuine, (v) all natural persons executing documents had and have the legal capacity to do so, (vi) all statements in certificates of public officials, managers, and officers of Equinix and Equinix Europe 2 Finco that we reviewed were and are accurate and (vii) all representations made by Equinix and Equinix Europe 2 Finco as to matters of fact in the documents that we reviewed were and are accurate.

Based upon the foregoing, and subject to the additional assumptions and qualifications set forth below, we advise you that, in our opinion:

In connection with the opinions expressed above, we have assumed that, at or prior to the time of the delivery of any such security, (i) the Board of Directors of Equinix and the Managers of Equinix Europe 2 Finco, as the case may be shall have duly established the terms of such security and duly authorized the issuance and sale of such security and such authorization shall not have been modified or rescinded; (ii) each of Equinix and Equinix Europe 2 Finco is, and shall remain, validly existing as an entity in good standing under the laws of the State of Delaware; (iii) the Post-Effective Amendment shall have become effective and such effectiveness shall not have been terminated or rescinded; (iv) the shares of Common Stock will not be issued or transferred in violation of any restriction or limitation contained in Article XI of Equinix’s Amended and Restated Certificate of Incorporation, as amended (the “Charter”); (v) upon the issuance of shares of Common Stock under the Equity Distribution Agreement, the total number of shares of Common Stock issued and outstanding will not exceed the total number of shares of Common Stock that Equinix is then authorized to issue under the Charter; (vi) the Base Indenture, any supplemental indenture, the Debt Securities, and the Equity Distribution Agreement are each valid, binding and enforceable agreements of each party thereto (other than as expressly covered above in respect of Equinix and Equinix Europe 2 Finco); and (vii) there shall not have occurred any change in law affecting the validity or enforceability of such security. We have also assumed that (i) the terms of any security whose terms are established subsequent to the date hereof and the issuance, execution, delivery and performance by Equinix or Equinix Europe 2 Finco of any such security (a) require no action by or in respect of, or filing with, any governmental body, agency or official and (b) do not contravene, or constitute a default under, any provision of applicable law or public policy or regulation or any judgment, injunction, order or decree or any agreement or other instrument binding upon Equinix or Equinix Europe 2 Finco.

We are members of the Bars of the States of New York and California, and the foregoing opinion is limited to the laws of the State of New York and the General Corporation Law of the State of Delaware.

We hereby consent to the filing of this opinion as an exhibit to the Post-Effective Amendment referred to above and further consent to the reference to our name under the caption “Legal Matters” in the prospectus and the ATM Prospectus Supplement, which is a part of the Post-Effective Amendment. In giving this consent, we do not admit that we are in the category of persons whose consent is required under Section 7 of the Securities Act.

Very truly yours,

/s/ Davis Polk & Wardwell LLP