Exhibit 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We hereby consent to the incorporation by reference in the Registration Statements on Form S-8 (Nos. 333-45280, 333-58074, 333-71870, 333-85202, 333-104078, 333-113765, 333-117892, 333-122142, 333-132466, 333-140946, 333-149452, and 333-157545) of Equinix, Inc. of our report dated February 22, 2010 relating to the financial statements and the effectiveness of internal control over financial reporting, which appears in this Form 10-K.

San Jose, California

February 22, 2010